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期刊論文
  1. Cheng-Kai Lee; Fu-Ting Wang; Chien-Hsun Huang; Wen-Hsiung Chan* , “Prevention of methylmercury-triggered ROS-mediated impairment of embryo development by co-culture with adult adipose-derived mesenchymal stem cells” , 2024 , Toxicology Research , vol.0 , p.0-0. (SCI期刊)
  2. Cheng-Kai Lee; Fu-Ting Wang; Chien-Hsun Huang; Wen-Hsiung Chan* , “Role of activated p21-activated kinase 2 in methylmercury-induced embryotoxic effects on mouse blastocysts” , 2023 , Toxicology Research , vol.12 , p.433-445. (SCI期刊)
  3. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Role of caspase-3-cleaved/activated PAK2 in brusatol-triggered apoptosis of human lung cancer A549 cells” , 2022 , Toxicology Research , vol.11 , p.791-803. (SCI期刊)
  4. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Enniatin B induces dosage-related apoptosis or necrosis in mouse blastocysts leading to deleterious effects on embryo development” , 2022 , Drug and Chemical Toxicology , vol.45 , p.1449-1460. (SCI期刊)
  5. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Low-dose silver nanoparticles plus methyl mercury exert embryotoxic effects on mouse blastocysts via endoplasmic reticulum stress and mitochondrial apoptosis” , 2022 , Toxicology Research , vol.11 , p.460-474. (SCI期刊)
  6. Ko-Tung Chang; Yu-Ting Su; Yi-Ru Tsai; Kuo-Chung Lan; Yan-Der Hsuuw; Hong-Yo Kang; Wen-Hsiung Chan**; Fu-Jen Huang* , “High levels estradiol affect blastocyst implantation and post-implantation development directly in mice” , 2022 , Biomedical Journal , vol.45 , p.179-189. (SCI期刊)
  7. Chien-Hsun Huang; Fu-Ting Wang; Yan-Der Hsuuw, Fu-Jen Huang; Wen-Hsiung Chan* , “Non-embryotoxic dosage of alternariol aggravates ochratoxin A-triggered deleterious effects on embryonic development through ROS-dependent apoptotic processes” , 2021 , Toxicology Research , vol.10 , p.1211-1222. (SCI期刊)
  8. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Alternariol exerts embryotoxic and immunotoxic effects on mouse blastocysts through ROS-mediated apoptotic processes ” , 2021 , Toxicology Research , vol.10 , p.719-732. (SCI期刊)
  9. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Dose-dependent beneficial and harmful effects of berberine on mouse oocyte maturation and fertilization and fetal development” , 2020 , Toxicology Research , vol.9 , p.431-443. (SCI期刊)
  10. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Dosage-related beneficial and deleterious effects of ginsenoside Rb1 on mouse oocyte maturation and fertilization and fetal development” , 2019 , Environmental Toxicology , vol.34 , p.1001-1012. (SCI期刊)
  11. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Prevention of ochratoxin A-induced oxidative stress-mediated apoptotic processes and impairment of embryonic development in mouse blastocysts by liquiritigenin” , 2019 , Environmental Toxicology , vol.34 , p.573-584. (SCI期刊)
  12. Chien-Hsun Huang; Fu-Ting Wang; Wen-Hsiung Chan* , “Enniatin B1 exerts embryotoxic effects on mouse blastocysts and induces oxidative stress and immunotoxicity during embryo development” , 2019 , Environmental Toxicology , vol.34 , p.48-59. (SCI期刊)
  13. Chien-Hsun Huang; Jui-Ming Yeh#; Wen-Hsiung Chan* , “Hazardous impacts of silver nanoparticles on mouse oocyte maturation and fertilization and fetal development through induction of apoptotic processes” , 2018 , Environmental Toxicology , vol.33 , p.1039-1049. (SCI期刊)
  14. Chien-Hsun Huang; Zi-Wei Huang; Feng-Ming Ho; Wen-Hsiung Chan* , “Berberine impairs embryonic development in vitro and in vivo through oxidative stress-mediated apoptotic processes” , 2018 , Environmental Toxicology , vol.33 , p.280-294. (SCI期刊)
  15. Chien-Hsun Huang; Wen-Hsiung Chan* , “Protective Effects of Liquiritigenin against Citrinin-Triggered Oxidative Stress-Mediated Apoptosis and Disruption of Embryonic Development in Mouse Blastocysts” , 2017 , International Journal of Molecular Sciences , vol.18 , p.1-18. (SCI期刊)
  16. Chien-Hsun Huang; Wen-Hsiung Chan* , “Rhein Induces Oxidative Stress and Apoptosis in Mouse Blastocysts and Has Immunotoxic Effects during Embryonic Development” , 2017 , International Journal of Molecular Sciences , vol.18 , p.2018-2035. (SCI期刊)
  17. Bugi Ratno Budiarto; Wen-Hsiung Chan* , “Oxidative stresses-mediated apoptotic effects of ginsenoside Rb1 on pre- and post-implantation mouse embryos in vitro and in vivo” , 2017 , Environmental Toxicology , vol.32 , p.1990-2003. (SCI期刊)
  18. Madonna Rica Anggelia; Wen-Hsiung Chan* , “Impairment of preimplantation and postimplantation embryonic development through intrinsic apoptotic processes by ginsenoside Rg1 in vitro and in vivo” , 2017 , Environmental Toxicology , vol.32 , p.1937-1951. (SCI期刊)
  19. Fu-Jen Huang; Wen-Hsiung Chan* , “Apoptotic effects on maturation of mouse oocytes, fertilization, and fetal development by puerarin” , 2016 , Drug and Chemical Toxicology , vol.39 , p.380-387. (SCI期刊)
  20. Fu-Jen Huang; Wen-Hsiung Chan* , “Effects of ochratoxin A on mouse oocyte maturation and fertilization, and apoptosis during fetal development” , 2016 , Environmental Toxicology , vol.31 , p.724-735. (SCI期刊)
  21. Yan-Der Hsuuw; Wen-Hsiung Chan* , “Apoptotic effects of dillapiole on maturation of mouse oocytes, fertilization, and fetal development” , 2015 , Drug and Chemical Toxicology , vol.38 , p.469-476. (SCI期刊)
  22. Wen-Hsiung Chan* , “Hazardous Effects of Sanguinarine on Maturation of Mouse Oocytes, Fertilization, and Fetal Development Through Apoptotic Processes” , 2015 , Environmental Toxicology , vol.0 , p.0-0. (SCI期刊)
  23. Yu-Ching Fan; Wen-Hsiung Chan* , “ Epigallocatechin gallate induces embryonic toxicity in mouse blastocysts through apoptosis” , 2014 , Drug and Chemical Toxicology , vol.37 , p.247-254. (SCI期刊)
  24. Wen-Hsiung Chan , “Cytotoxic Effects of Dillapiole on Embryonic Development of Mouse Blastocysts in Vitro and in Vivo” , 2014 , International Journal of Molecular Sciences , vol.15 , p.10751-10765. (SCI期刊)
  25. Fu-Jen Huang; Yan-Der Hsuuw; Wen-Hsiung Chan* , “Characterization of apoptosis induced by emodin and related regulatory mechanisms in human neuroblastoma cells” , 2013 , International Journal of Molecular Sciences , vol.14 , p.20139-20156. (SCI期刊)
  26. Fu-Jen Huang, Ting-Yu Chin and Wen-Hsiung Chan* , “Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocysts” , 2013 , Environmental Toxicology , vol.28 , p.431-441. (SCI期刊)
  27. I-Meng Huang; Wen-Hsiung Chan* , “Impact of 2-bromopropane on mouse embryonic stem cells and related regulatory mechanisms” , 2013 , African Journal of Biotechnology , vol.12 , p.3012-3022.
  28. Fu-Jen Huang*, Kuo-Chung Lan, Hong-Yo Kang, Pin-Yao Lin, Wen-HsiungChan**, Yu-Cheng Hsu, Yen-Chih Liu, Ko-En Huang , “Retinoic Acid Influences the Embryoid Body Formation in Mouse Embryonic Stem Cells by Induction of Caspase and p38 MAPK/JNK-Mediated Apoptosis.” , 2013 , Environ. Toxicol. , vol.28 , p.190-200. (SCI期刊)
  29. Wen-Hsiung Chan, Wei-Li Houng, Cheng-An J. Lin, Chih-Hsien Lee,Po-Wen Li, Jyun-Tai Hsieh, Ji-Lin Shen, Hung-I Yeh, Walter H. Chang* , “Impact of dihydrolipoic acid on mouse embryonic stem cells and related regulatory mechanisms” , 2013 , Environ. Toxicol. , vol.28 , p.87-97. (SCI期刊)
  30. GW Shu; CH Chiu; LT Huang; TN Lin; CC Yang; JS Wang; CT Yuan; JL Shen; HC Kuo; CA Lin; WH Chang; HH Wang; HI Yeh; WH Chan; WC Fan; WC Chou , “ Efficient energy transfer from InGaN quantum wells to Ag nanoparticles” , 2013 , Physical chemistry chemical physics , vol.15 , p.3618-3622. (SCI期刊)
  31. Fu-Jen Huang*; Kuo-Chung Lan; Hong-Yo Kang; Yen-Chih Liu; Yan-Der Hsuuw; Wen-Hsiung Chan*; Ko-En Huang , “Effect of curcumin on in vitro early post-implantation stages of mouse embryo development” , 2013 , European Journal of Obstetrics & Gynecology and Reproductive Biology , vol.166 , p.47-51. (SCI期刊)
  32. Yan-Der Hsuuw; Wen-Hsiung Chan *; Jau-Song Yu , “Ochratoxin A Inhibits Mouse Embryonic Development by Activating a Mitochondrion-Dependent Apoptotic Signaling Pathway” , 2013 , International Journal of Molecular Sciences , vol.14 , p.935-953. (SCI期刊)
  33. Mei-Hui Chang; Shao-Chung Chang; Wen-Hsiung Chan* , “Injurious effects of emodin on maturation of mouse oocytes, fertilization, and fetal development via apoptosis” , 2012 , International Journal of Molecular Sciences , vol.13 , p.13911-13925. (SCI期刊)
  34. Mei-Hui Chang; Fu-Jen Huang; Wen-Hsiung Chan* , “Emodin induces embryonic toxicity in mouse blastocysts through apoptosis” , 2012 , Toxicology , vol.299 , p.25-32. (SCI期刊)
  35. Cheng-An J. Lin*, Wen-Kai Chuang, Zih-Yun Huang, Shih-Tsung Kang, Ching-Yi Chang,Ching-Ta Chen, Jhih-Liang Li, Jimmy K. Li,, Hsueh-Hsiao Wang,Fu-Chen Kung, Ji-Lin Shen, Wen-Hsiung Chan, Chih-Kuang Yeh,Hung-I Yeh,Wen-Fu T. Lai*, Walter H. Chang* , “Rapid transformation of protein-caged nanomaterials into microbubbles as bimodal imaging agents” , 2012 , ACS Nano , vol.6 , p.5111-5121. (SCI期刊)
  36. I-Meng Huang; Wen-Hsiung Chan* , “Resveratrol protects against hazardous effects of 2-bromopropane on maturation of mouse oocytes, fertilization and fetal development” , 2012 , African Journal of Biotechnology , vol.11 , p.10262-10271. (SCI期刊)
  37. Chia-Chi Chen; Wen-Hsiung Chan* , “Injurious Effects of Curcumin on Maturation of Mouse Oocytes, Fertilization and Fetal Development via Apoptosis” , 2012 , International Journal of Molecular Sciences , vol.13 , p.4655-4672. (SCI期刊)
  38. Wei-Li Houng, Cheng-An J. Lin, Ji-Lin Shen, Hung-I Yeh, Hsueh-Hsiao Wang, Walter H. Chang, Wen-Hsiung Chan* , “Dihydrolipoic Acid Induces Cytotoxicity in Mouse Blastocysts through Apoptosis Processes” , 2012 , International Journal of Molecular Sciences , vol.13 , p.3988-4002. (SCI期刊)
  39. Wen-Hsiung Chan* , “Embryonic toxicity of sanguinarine through apoptotic processes in mouse blastocysts.” , 2011 , Toxicol. Lett. , vol.205 , p.285-292. (SCI期刊)
  40. Wen-Hsiung Chan* , “Resveratrol protects against 2-Bromopropane-induced apoptosis and disruption of embryonic development in blastocysts” , 2011 , Int. J. Mol. Sci. , vol.12 , p.4991-5010. (SCI期刊)
  41. Hsueh-Hsiao Wang, Cheng-An J. Lin, Chih-Hsien Lee, Yi-Chun Lin, Ya-Ming Tseng, Chin-Ling Hsieh, Chih-Hao Chen, Cheng-Ho Tsai, Chun-Tai Hsieh, Ji-Lin Shen, Wen-Hsiung Chan, Walter H. Chang*,Hung-I Yeh* , “Fluorescent Gold Nanoclusters as a Biocompatible Marker for In Vitro and In Vivo Tracking of Endothelial Cells” , 2011 , ACS Nano , vol.5 , p.4337-4344. (SCI期刊)
  42. Wen-Hsiung Chan* , “Photodynamic Treatment Induces an Apoptotic Pathway Involving Calcium, Nitric Oxide, p53, p21-Activated Kinase 2, and c-Jun N-terminal kinase and Inactivates Survival Signal in Human Umbilical Vein Endothelial Cells” , 2011 , Int. J. Mol. Sci. , vol.12 , p.1041-1059. (SCI期刊)
  43. Wen-Hsiung Chan* , “Hazardous Apoptotic Effects of 2-Bromopropane on Maturation of Mouse Oocytes, Fertilization, and Fetal Development” , 2010 , Int. J. Mol. Sci. , vol.11 , p.4361-4380. (SCI期刊)
  44. Shu, G.-W., Chen, T.-Y., Shen, J.- L., Lin, C. A. J., Chang, W.-H., Chan, W.-H., Wang, H.-H., Yeh, H.-I., Chou, W.-C. , “Interrelation of transport and optical properties in gold nanoclusters” , 2010 , Applied Physics Letters , vol.97 , p.123108-1-123108-3. (SCI期刊)
  45. Po-Wn Li, Tai-Hung Kuo, Ji-Hao Chang, Jui-Ming Yeh*, Wen-Hsiung Chan* , “Induction of cytotoxicity and apoptosis in mouse blastocysts by silver nanoparticles” , 2010 , Toxicol. Lett. , vol.197 , p.82-87. (SCI期刊)
  46. Chia-Chi Chen, Ming-Shu Hsieh, Yan-Der Hsuuw, Fu-Jen Huang*, Wen-Hsiung Chan* , “Hazardous Effects of Curcumin on Mouse Embryonic Development Through a Mitochondria-Dependent Apoptotic Signaling Pathway” , 2010 , Int. J. Mol. Sci. , vol.11 , p.2839-2855. (SCI期刊)
  47. Jimmy Kuan -Jung Li, Cheng- An J. Lin, Hsiao-Yun Wu, Wen-Hsiung Chan, Walter Hong-Shong Chang* , “Detection of Curcumin-induced Osteoblasts Apoptosis using Quantum Dot Probes” , 2010 , Journal of Medical and Biological Engineering , vol.30 , p.221-226. (SCI期刊)
  48. Hsiao-Chen Tu, Chih-Ping Chen, Wen-Hsiung Chan* , “Epicatechin gallate decreases the viability and sequent embryonic development of mouse blastocysts” , 2010 , Taiwan J. Obstet. Gynecol. , vol.49 , p.174-180. (SCI期刊)
  49. Ying-Jing Chang, Wen-Hsiung Chan* , “Methylglyoxal has injurious effects on maturation of mouse oocytes, fertilization, and fetal development, via apoptosis” , 2010 , Toxicol. Lett. , vol.193 , p.217-223. (SCI期刊)
  50. Wen-Hsiung Chan* , “Cytotoxic Effects of 2-Bromopropane on Embryonic Development in Mouse Blastocysts” , 2010 , Int. J. Mol. Sci. , vol.11 , p.731-744. (SCI期刊)
  51. Chia-Chi Chen and Wen-Hsiung Chan* , “Impact Effects of Puerarin on Mouse Embryonic Development” , 2009 , Reproductive Toxicology , vol.28 , p.530-535. (SCI期刊)
  52. Yu-Ting Huang, Ching-Yu Lai, Shyhliang Lou, Jui-Ming Yeh, Wen-Hsiung Chan* , “Activation of JNK and PAK2 is Essential for Citrinin-Induced Apoptosis in a Human Osteoblast Cell Line” , 2009 , Environmental Toxicology , vol.24 , p.343-356. (SCI期刊)
  53. Yan-Der Hsuuw; Tzong-Fu Kuo; Kun-Hsiung Lee; Yen-Chih Liu; Yu-Ting Huang; Wen-Hsiung Chan* , “Ginkgolide B Induces Apoptosis via Activation of JNK and PAK2 in Mouse Embryonic Stem Cells” , 2009 , Annals of the New York Academy of Sciences , vol.1171 , p.501-508. (SCI期刊)
  54. Wen-Hsiung Chan* , “Impact of Genistein on Maturation of Mouse Oocytes, Fertilization, and Fetal Development” , 2009 , Reproductive Toxicology , vol.28 , p.52-58. (SCI期刊)
  55. Nion-Heng Shiao and Wen-Hsiung Chan* , “Injury Effects of Ginkgolide B on Maturation of Mouse Oocytes, Fertilization, and Fetal Development in vitro and in vivo” , 2009 , Toxicology Letters , vol.188 , p.63-69. (SCI期刊)
  56. Chia-Chi Chen and Wen-Hsiung Chan* , “Inhibition of Citrinin-Induced Apoptotic Biochemical Signaling in Human Hepatoma G2 Cells by Resveratrol” , 2009 , International Journal of Molecular Science , vol.10 , p.3338-3357. (SCI期刊)
  57. Ming-Shu Hsieh; Nion-Heng Shiao; Wen-Hsiung Chan* , “Cytotoxic Effects of CdSe Quantum Dots on Maturation of Mouse Oocytes, Fertilization, and Fetal Development” , 2009 , Int. J. Mol. Sci. , vol.10 , p.2122-2135. (SCI期刊)
  58. Ming-Shu Hsieh and Wen-Hsiung Chan* , “Impact of Methylglyoxal and High Glucose Co-treatment on Human Mononuclear Cells” , 2009 , International Journal of Molecular Science , vol.10 , p.1445-1464. (SCI期刊)
  59. M. D. Yang; Y. K. Liu; J. L. Shen*; C. H. Wu; C. A. Lin; W. H. Chang; H. H. Wang; H. I. Yeh; W. H. Chan; W. J. Parak , “Improvement of conversion efficiency for multijunction solar cells by incorporation of Au nanoclusters” , 2008 , Optics Express , vol.16 , p.15754-15758. (SCI期刊)
  60. Wen-Hsiung Chan* , “Effects of Citrinin on Maturation of Mouse Oocytes, Fertilization, and Fetal Development in vitro and in vivo” , 2008 , Toxicology Letters , vol.180 , p.28-32. (SCI期刊)
  61. Pin-Zhen Lu, Ching-Yu Lai, Wen-Hsiung Chan* , “Caffeine Induces Cell Death via Activation of Apoptotic Signal and Inactivation of Survival Signal in Human Osteoblasts” , 2008 , Int. J. Mol. Sci. , vol.9 , p.698-718. (SCI期刊)
  62. Mei-Hui Ni, Chih-Ching Wu, Wen-Hsiung Chan, Kun-Yi Chien, Jau-Song Yu* , “GSK-3 Mediates the Okadaic Acid-Induced Modification of Collapsin Response Mediator Protein-2 In Human SK-N-SH Neuroblastoma Cells” , 2008 , J Cell. Biochem. , vol.103 , p.1833-1848. (SCI期刊)
  63. Wen-Hsiung Chan*, Hsin-Jung Wu , “Methylglyoxal and High Glucose Co-treatment Induces Apoptosis or Necrosis in Human Umbilical Vein Endothelial Cells” , 2008 , Journal of Cellular Biochemistry , vol.103 , p.1144-1157. (SCI期刊)
  64. Wen-Hsiung Chan* , “Citrinin Induces Apoptosis in Mouse Embryonic Stem Cells” , 2008 , IUBMB Life , vol.60 , p.171-179. (SCI期刊)
  65. Wen-Hsiung Chan*, Nion-Heng Shiao , “Cytotoxic Effect of CdSe Quantum Dots on Mouse Embryonic Development” , 2008 , Acta Pharmacologica Sinica , vol.28 , p.259-266. (SCI期刊)
  66. Wen-Hsiung Chan*, Nion-Heng Shiao , “Effect of Citrinin on Mouse Embryonic Development in Vitro and in Vivo” , 2007 , Reproductive Toxicology , vol.24 , p.120-125. (SCI期刊)
  67. Lien-Hung Huang, Nion-Heng Shiao, Yan-Der Hsuuw, Wen-Hsiung Chan* , “Protective Effects of Resveratrol on Ethanol-induced Apoptosis in Embryonic Stem Cells and Disruption of Embryonic Development in Mouse Blastocysts” , 2007 , Toxicology , vol.242 , p.109-122. (SCI期刊)
  68. Wen-Hsiung Chan* , “The Signaling Cascades of Ginkgolide B-Induced Apoptosis in MCF-7 Breast Cancer Cells” , 2007 , International Journal of Molecular Sciences , vol.8 , p.1177-1195. (SCI期刊)
  69. Wen-Hsiung Chan* , “Citrinin Induces Apoptosis via a Mitochondria-Dependent Pathway and Inhibition of Survival Signals in Embryonic Stem Cells, and Causes Developmental Injury in Blastocysts” , 2007 , Biochemical Journal , vol.404 , p.317-326. (SCI期刊)
  70. Nion-Heng Shiao, Hsiang-Yu Lu, Wen-Hsiung Chan* , “Dosage Effect of CdSe Quantum Dots-Induced Cell Death Mode in Human Mononuclear Cells” , 2007 , Journal of Medical and Biological Engineering , vol.27 , p.97-104. (EI期刊)
  71. Hsin-Jung Wu, Wen-Hsiung Chan* , “Genistein Protects Methylglyoxal-Induced Oxidative DNA Damage and Cell Injury in Human Mononuclear Cells” , 2007 , Toxicology in Vitro , vol.21 , p.335-342. (SCI期刊)
  72. Wen-Hsiung Chan*, Hsin-Jung Wu, Nion-Heng Shiao , “Apoptotic Signaling in Methylglyoxal-treated Human Osteoblasts Involves Oxidative Stress, c-Jun N-terminal Kinase, Caspase-3, and p21-Activated Kinase 2” , 2007 , Journal of Cellular Biochemistry , vol.100 , p.1056-1069. (SCI期刊)
  73. Wen-Hsiung Chan*, Hsiang-Yu Lu, Nion-Heng Shiao , “Effect of Genistein on Mouse Blastocyst Development in Vitro” , 2007 , Acta Pharmacologica Sinica , vol.28 , p.238-245. (SCI期刊)
  74. Wen-Hsiung Chan*, Yan-Der Hsuuw , “Dosage Effects of Ginkgolide B on Ethanol-Induced Cell Death in Human Hepatoma G2 Cells” , 2007 , Ann. NY Acad. Sci. , vol.1095 , p.388-398. (SCI期刊)
  75. Yan-Der Hsuuw, Wen-Hsiung Chan* , “Epigallocatechin Gallate Dose-Dependently Induces Apoptosis or Necrosis in Human MCF-7 Cells” , 2007 , Ann. NY Acad. Sci. , vol.1095 , p.428-440. (SCI期刊)
  76. Wen-Hsiung Chan*, Nion-Heng Shiao, Pin-Zhen Lu , “CdSe Quantum Dots Induce Apoptosis in Human Neuroblastoma Cells via Mitochondrial-Dependent Pathways and Inhibition of Survival Signals” , 2006 , Toxicology Letters , vol.167 , p.191-200. (SCI期刊)
  77. Wen-hsiung Chan , “Ginkgolide B Induces Apoptosis and Developmental Injury in Mouse Embryonic Stem Cells and Blastocysts” , 2006 , Human Reproduction , vol.21 , p.2985-2995. (SCI期刊)
  78. Wen-Hsiung Chan*, Hsin-Jung Wu , “Protective Effects of Curcumin on Methylglyoxal-Induced Oxidative DNA Damage and Cell Injury in Human Mononuclear Cells.” , 2006 , Acta Pharmacol. Sin. , vol.27 , p.1192-1198. (SCI期刊)
  79. Wen-Hsiung Chan, Hsiao-Yun Wu, Walter Hong-Shong Chang , “Dosage Effects of Curcumin on Cell Death Types in a Human Osteoblast Cell Line” , 2006 , Food and Chemical Toxicology , vol.44 , p.1362-1371. (SCI期刊)
  80. Hsiang-Yu Lu, Nion-Heng Shiao, Wen-Hsiung Chan* , “CdSe Quantum Dots Induce Apoptosis via Activation of JNK and PAK2 in a Human Osteoblast Cell Line” , 2006 , Journal of Medical and Biological Engineering , vol.26 , p.89-96. (EI期刊)
  81. Wen-Hsiung Chan*, Ying-Jing Chang , “Dosage Effects of Resveratrol on Ethanol-Induced Cell Death in the Human K562 Cell Line” , 2006 , Toxicology Letters , vol.161 , p.1-9. (SCI期刊)
  82. Wen-Hsiung Chan* , “Ginkgolides Induce Apoptosis and Decrease Cell Numbers in Mouse Blastocysts” , 2005 , Biochem. Biophys. Res. Commun. , vol.338 , p.1263-1267. (SCI期刊)
  83. Yan-Der Hsuuw, Chen-Kang Chang, Wen-Hsiung Chan*, Jau-Song Yu (*correspondence author) , “Curcumin Prevents Methylglyoxal-Induced Oxidative Stress and Apoptosis in Mouse Embryonic Stem Cells and Blastocysts” , 2005 , Journal of Cellular Physiology , vol.205 , p.379-386. (SCI期刊)
  84. Wen-Hsiung Chan* , “Resveratrol Induced Apoptosis in Human Cervix Epithelial Carcinoma Cells” , 2005 , 台灣農業化學與食品科學 , vol.43 , p.325-332.
  85. Wen-Hsiung Chan*, Hsin-Jung Wu, Yan-Der Hsuuw , “Curcumin Inhibits ROS Formation and Apoptosis in Methylglyoxal-Treated Human Hepatoma G2 Cells” , 2005 , Ann. N.Y. Acad. Sci. , vol.1042 , p.371-378. (SCI期刊)
  86. Wen-Hsiung Chan* , “Effect of Resveratrol on High Glucose-Induced Stress in Human Leukemia K562 Cells.” , 2005 , Journal of Cellular Biochemistry , vol.94 , p.1267-1279. (SCI期刊)
  87. Wen-Hsiung Chan* , “The Antiapoptotic Effect of Soybean Genistein on Hydrogen Peroxide Treated Balb/c 3T3 Cells.” , 2004 , 台灣農業化學與食品科學 (J. Argi. Chem. and Food Sci.) , vol.42 , p.403-410.
  88. Wen-Hsiung Chan*, Hsin-Jung Wu , “Antiapoptotic Effects of Curcumin on Photosensitized Human Epidermal Carcinoma A431 Cells” , 2004 , Journal of Cellular Biochemistry , vol.92 , p.200-212. (SCI期刊)
  89. Wen-Hsiung Chan* , “Inhibition of Apoptotic Signaling Cascade in Photosensitized Human Epidermal Carcinoma A431 Cells by Genistein.” , 2004 , Chung Yuan Journal （中原學報） , vol.32 , p.1-7.
  90. Wen-Hsiung Chan, Chih-Ching Wu, Jau-Song Yu , “Curcumin Inhibits UV Irradiation-Induced Oxidative Stress and Apoptotic Biochemical Changes in Human Epidermoid Carcinoma A431 Cells” , 2003 , Journal of Cellular Biochemistry , vol.90 , p.327-338. (SCI期刊)
  91. Chen-Kang Chang, Hung-Fu Tseng, Yan-Der Hsuuw, Wen-Hsiung Chan , “Higher LDL Oxidation at rest and after a regby game in weekend warriors” , 2002 , Nutrition & Metabolism , vol.0 , p.103-107. (SCI期刊)
  92. Jau-Song Yu*, Sheng-Hung Chang, Wen-Hsiung Chan, Hua-Chien Chen , “Enzyme-linked immunosorbent assay for the determination of p21-activated kinase activity.” , 2001 , J. Biochem. , vol.129 , p.243-251. (SCI期刊)
  93. Wen-Hsiung, Chan, Jau-Song Yu*, Shiaw-Der Yang , “Apoptotic signalling cascade in photosensitized human epidermal carcinoma cells: Involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3, and p21-Activated kinase 2” , 2000 , Biochem. J. , vol.351 , p.221-232. (SCI期刊)
  94. Wen-Hsiung Chan, Jau-Song Yu* , “Inhibition of UV irradiation-induced oxidative stresses and apoptotic biochemical changes in human epidermal carcinoma A431 cells by genistein.” , 2000 , J. Cell. Biochem. , vol.78 , p.73-84. (SCI期刊)
  95. Wen-Hsiung Chan, Jau-Song Yu, Shiaw-Der Yang* , “PAK2 is cleaved and activation during hyperosmotic shock-induced apoptosis via a caspase-dependent mechanism. Evidence for the involvement of oxidative stress.” , 1999 , J.Cell. Physiol. , vol.178 , p.397-408. (SCI期刊)
  96. Tswen-Kei Tang, Wen-Chang Chang, Wen-Hsiung Chan, Shiaw-Der Yang, Mei-Hui Ni, Jau-Song Yu* , “Proteolytic cleavage and activation of PAK2 during UV irradiation-induced apoptosis ” , 1998 , J. Cell. Biochem. , vol.70 , p.442-454. (SCI期刊)
  97. Jau-Song Yu*, Wei-Jen Chen, Mei-Hui Ni, Wen-Hsiung Chan, Shiaw-Der Yang , “Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase : Evidence that auto-kinase belongs to PAK family.” , 1998 , Biochem. J. , vol.334 , p.121-131. (SCI期刊)
  98. Wen-Hsiung Chan, Jau-Song Yu*, Shiaw-Der Yang , “Heat shock stress induces cleavage and activation of PAK2 in apoptotic cells.” , 1998 , J. Protein Chem. , vol.17 , p.485-494. (SCI期刊)
  99. Jau-Song Yu, Wen-Hsiung Chan, Shiaw-Der Yang , “Selective interaction of of protein kinase FA/GSK-3 alpha with membrane phospholipids.” , 1997 , Biochem. Biophys. Res. Commun. , vol.237 , p.331-335. (SCI期刊)
  100. Jau-Song Yu, Wen-Hsiung Chan, Shiaw-Der Yang , “Activation of the ATP.Mg-dependent type-1 protein phosphatase by the Fe2+/ascorbate system.” , 1996 , J. Protein Chem. , vol.15 , p.455-460. (SCI期刊)
  101. Shiaw-Der Yang, Jen-Shin Song, Hui-Wen Liu,Wen-Hsiung Chan , “Cyclic modulation of cross-linking interactions of microtubule-associated protein-2 with actin and microtubules by protein kinase FA.” , 1993 , J. Protein Chem. , vol.12 , p.393-402. (SCI期刊)
  102. Shiaw-Der Yang, Wen-Hsiung Chan, Hui-Wen Liu , “Cyclic modulation of cytoskeleton assembly-disassembly by the ATP.Mg-dependent protein phosphatase activator (kinase FA).” , 1993 , Biochem. Biophys. Res. Commun. , vol.193 , p.1202-1210. (SCI期刊)
  103. Shiaw-Der Yang, Jen-Shin Song, Y.-T. Hsieh,Hui-Wen Liu, Wen-Hsiung Chan , “Identification of the ATP.Mg-dependent protein phosphatase activator (FA) as a synapsine Ⅰ kinase that inhibits cross-linking of synapsine Ⅰ with brain microtubule.” , 1992 , J. Protein Chem. , vol.11 , p.539-546. (SCI期刊)
  104. Shiaw-Der Yang, Jen-Shin Song, Y.-T. Hsieh,Wen-Hsiung Chan, Hui-Wen Liu , “Cyclic inhibition-potentiation of the crosslinking of synapsine Ⅰ with brain microtubules by protein kinase FA (an activator of ATP.Mg-dependent protein phosphatase).” , 1992 , Biochem. Biophys. Res. Commun. , vol.184 , p.973-979. (SCI期刊)
研討會論文
  1. Wen-Hsiung Chan , “Dosage effects of berberine on cell death types in human lung adenocarcinoma A549 cells” , 2019 , Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment , 2019 /3 /15 ~ 2019 /3 /19 , Italian Republic .
  2. Bugi Ratno Budiarto; Wen-Hsiung Chan* , “Effects of ginsenoside Rb1 on mouse blastocysts and sequent embryonic development” , 2016 , The World Congress on Recurrent Pregnancy Loss (WCRPL) , 2016 /1 /14 ~ 2016 /1 /17 , France .
  3. Wen-Hsiung Chan*; Yan-Der Hsuuw , “Enniatins induces embryonic toxicity in mouse blastocysts through apoptosis” , 2015 , The 2015 Pregnancy Summit , 2015 /9 /29 ~ 2015 /10 /1 , United Kingdom .
  4. Yu-Ching Fan and Wen-Hsiung Chan* , “Hazardous effects of dillapiole on maturation of mouse oocytes, fertilization, and fetal development” , 2014 , The 2014 Pregnancy Summit , 2014 /10 /6 ~ 2014 /10 /8 , United Kingdom .
  5. Wen-Hsiung Chan* , “Enniatin has injurious effects on maturation of mouse oocytes, fertilization, and fetal development, via apoptosis.” , 2013 , OVARIAN CLUB III. The inverse pyramid: Regulating follicle number and oocyte quality , 2013 /11 /14 ~ 2013 /11 /16 , France .
  6. Wen-Hsiung Chan , “Induction of cytotoxicity and apoptosis in mouse blastocysts by enniatin” , 2013 , 12th European Fusarium Seminar: Fusarium – Mycotoxins, Taxonomy, Genomics, Biosynthesis, Pathogenicity, Resistance, Disease control , 2013 /5 /12 ~ 2013 /5 /16 , France .
  7. Wen-Hsiung Chan* , “Natural killer cell apoptotic signaling cascades in coronary artery disease” , 2011 , 9th international congress on coronary artery disease: from prevention to intervention , 2011 /10 /23 ~ 2011 /10 /26 .
  8. Chang, Y-J; Chan, W.-H.* , “Ginkgolide B Triggers Apoptotic Signaling Cascades In Human Hepatoma G2 Cells” , 2011 , The latest advances in liver cancer research: From basic to therapeutics , 2011 /3 /1 ~ 2011 /3 /3 .
  9. Hsieh, M.-S., Shiao, N.-H. and Chan, W.-H.* , “Hazardous Effects of Extremely Low Frequency Electromagnetic Fields on Embryonic Development of Mouse Blastocysts” , 2010 , 2010 First International Conference on Cellular, Molecular Biology, Biophysics and Bioengineering (CMBB 2010) , 2010 /12 /25 ~ 2011 /12 /26 .
  10. Chan, W.-H. , “High Glucose and Methylglyoxal Co-treatment Induces Apoptosis and Developmental Injury in Mouse Blastocysts” , 2010 , 2010 First International Conference on Cellular, Molecular Biology, Biophysics and Bioengineering (CMBB 2010) , 2010 /12 /25 ~ 2011 /12 /26 .
  11. Chan, W.-H.* and Chang, Y.-J. , “Arachidonic acid induces apoptosis via activation of JNK and PAK2 in human neuroblastoma cells” , 2010 , Keystone Symposia Conference: Bioactive Lipids-Biochemistry and Diseases , 2010 /6 /6 ~ 2010 /6 /11 .
  12. Huang, Y. T., Chan, W. H.* , “Caffeine Induces Apoptosis via Activation of JNK AND PAK2 in Mouse Embryonic Stem Cells” , 2008 , Targeting cell death pathways for human diseases , 2008 /6 /6 ~ 2008 /6 /9 .
  13. Hsuuw, Y. D., Kuo, T. F., Huang, F. J., Liu, Y. C., Lai, C. Y., Huang, Y. T., Chan, W. H.* , “High Glucose and Methylglyoxal Co-treatment Induces Apoptosis and Developmental Injury in Mouse Blastocysts” , 2008 , Apoptosis 2008: From mechanisms to applications , 2008 /1 /23 ~ 2008 /1 /26 .
  14. Hsuuw, Y. D., Kuo, T. F., Lee, K. H., Liu, Y. C., Huang, Y. T., Chan, W. H.* , “Ginkgolide B Induces Apoptosis via Activation of JNK and PAK2 in Mouse Embryonic Stem Cells” , 2008 , Apoptosis 2008: From mechanisms to applications , 2008 /1 /23 ~ 2008 /1 /26 .
  15. Chan, W. H. and Wu, H. J. , “Methylglyoxal and High Glucose Co-treatment Induces Apoptosis in Human Mononuclear Cells via Mitochondrial Membrane Potential Change” , 2007 , The Fourth Conference of Aseanian Membrane Society , 2007 ~ 2007 .
  16. Chan, W. H., Huang, L. H., Shiao, N. H. , “Protection Effects of Resveratrol on Ethanol-Induced Cell Apoptosis in Mouse Blastocysts” , 2007 , Apoptotic and Non-Apoptotic Cell Death Pathways , 2007 /4 /15 ~ 2007 /4 /20 .
  17. Chan, W. H.*, Chang, Y. J. , “Effects of Resveratrol on Ethanol-Induced Cell Death in Human Hepatoma G2 Cells” , 2006 , BioScience2006-bioscience for the 21st century , 2006 /7 /23 ~ 2006 /7 /27 .
  18. Chan, W. H.*, Chang, Y. J. , “Impact Effects of Resveratrol on Ethanol-Induced Cell Death in Mouse Embryonic Stem Cells” , 2006 , 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress , 2006 /6 /18 ~ 2006 /6 /23 .
  19. L. H. Huang, N. H. Shiao, W. H. Chan* , “Inhibition of Ethanol-Induced Cell Apoptosis in Mouse Blastocysts by Resveratrol” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  20. N. H. Shiao, L. H. Huang, W. H. Chan* , “Effect of Electromagnetic Field Treatment on Cell Death and Embryonic Development in Mouse Blastocysts” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  21. Ching-Yu Lai, Wen-Hsiung Chan* , “The Apoptotic Biochemical Changs in Resveratrol-treated Human MCF-7 Cell Line” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  22. Yu-Jiyun Hsu, Wen-Hsiung Chan* , “Effect of Curcumin on Methylglyoxal-Induced Stress on Mononuclear Cells” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  23. Hsiang-Yu Lu, Wen-Hsiung Chan* , “Caffeine Induces Oxidative Stress Generation and Cytotoxicity in Human Osteoblasts” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  24. Hsiu-Hua Wang, Wen-Hsiung Chan* , “Curcumin Induces Apoptotic Biochemical Changes in Human Epidermal Carcinoma A431 Cells” , 2006 , The 21th Joint Annual Conference of Biomedical Sciences (2006) , 2006 /3 /18 ~ 2006 /3 /19 .
  25. Hsuuw Y. D. and Chan, W. H.* , “Epigallocatechin Gallate Dose-Dependently Induces Apoptosis or Necrosis in Human MCF-7 Cells.” , 2006 , Cell Signaling World 2006 – Luxembourg: Signal Transduction Pathways as therapeutic targets , 2006 /1 /25 ~ 2006 /1 /28 .
  26. Chan, W. H.* and Hsuuw Y. D. , “Dosage Effects of Ginkgolide B on Ethanol-Induced Cell Death in Human Hepatoma G2 Cells” , 2006 , Cell Signaling World 2006 – Luxembourg: Signal Transduction Pathways as therapeutic targets , 2006 /1 /25 ~ 2006 /1 /28 .
  27. Lien-Hung Huang, Nion-Heng Shiao, Wen-Hsiung Chan* , “Protection Effects of Resveratrol on Ethanol-Induced Cell Apoptosis in Mouse Blastocysts” , 2006 , Fourteenth Symposium on Recent Advances in Cellular and Molecular Biology , 2006 /1 /18 ~ 2006 /1 /20 .
  28. Ching-Yu Lai, Wen-Hsiung Chan* , “Resveratrol Induces Cell apoptosis in a Human MCF-7 Cell Line” , 2006 , Fourteenth Symposium on Recent Advances in Cellular and Molecular Biology , 2006 /1 /18 ~ 2006 /1 /20 .
  29. Nion-Heng Shiao, Lien-Hung Huang, Wen-Hsiung Chan* , “Electromagnetic Field Induces Cell Death and Decrease Cell Number in Mouse Blastocysts” , 2006 , Fourteenth Symposium on Recent Advances in Cellular and Molecular Biology , 2006 /1 /18 ~ 2006 /1 /20 .
  30. Lu, H.-Y., Shiao, N.-H., Chan, W.-H. , “PAK2 Is Activated during CdSe Quantum Dots-induced Apoptosis via A Caspase-dependent Mechanism” , 2005 , 2005 Nano Bioengineering International Symposium , 2005 /12 /15 ~ 2005 /12 /16 .
  31. Wen-Hsiung Chan , “Dosage Effects of Resveratrol on Ethanol-Induced Cell Injury in Mouse Embryonic Stem Cells” , 2005 , Keystone Symposia: Stem Cells, Senescence and Cancer , 2005 /10 /25 ~ 2005 /10 /30 .
  32. 詹文雄 , “白藜蘆醇誘導細胞凋亡機制的探討” , 2005 , 2005年全球華人保健食品科技大會:挑戰21世紀保健食品產業 , 2005 /6 /18 ~ 2005 /6 /19 .
  33. Wu, H-Y, Chan, W.-H., Lin J., Chang, W.-H. , “Dosimetry Effect of Curcumin with Different Concentrations on Osteoblasts Cell Line-hFob1.19” , 2004 , Biomedical Engineering Society Annual Symposia , 2005 /12 ~ 2005 /12 .
  34. Chen, Y.-H., Chan, W.-H., Lin, J., Chang, W. H. , “Dosimetry Effect of Retinoic Acid with Different Concentrations on Osteoblast Cell line-hFob1.19” , 2004 , Biomedical Engineering Society Annual Symposia , 2004 /12 ~ 2004 /12 .
  35. Chan, W-H , “Antiapoptotic Effects of Resveratrol on Hyperosmotic Shock-Treated Human Hepatoma 3B Cells” , 2004 , 17th FAOBMB Symposium / 2nd IUBMB Special Meeting / 7th A-IMBN Conference: Genomics and Health in the 21st Century , 2004 /11 /22 ~ 2004 /11 /26 .
  36. Wen-Hsiung Chan , “Resveratrol Attenuates Hyperosmotic Shock-Induced Apoptotic Biochemical Changes in Human Hepatoma 3B Cells” , 2004 , BioScience2004-from molecules to organisms , 2004 /7 /18 ~ 2004 /7 /22 .
  37. Chan, W-H , Wu, H-J , Hsuuw,Y-D , “Curcumin Protects Human Hepatoma G2 Cells to ROS-Mediated Methylglyoxal Injury” , 2004 , 2nd Conference of Asia Society for Mitochondrial Research and Medicine , 2004 /4 /1 ~ 2004 /4 /2 .
  38. Chan, W.-H. and Wu, H.-J. , “薑黃素抗氧化壓力與防止細胞凋亡的研究” , 2003 , 2003全球華人保健（功能）食品科技大會 , 2003 /12 /9 ~ 2003 /12 /10 .
  39. Wen-Hsiung Chan , Chih-Ching Wu, Jau-Song Yu , “The Signal Transducing Pathway of UV-Induced Apoptosis in Human Epidermal Carcinoma A431 Cells” , 2003 , 8th Biomedical Material and Technology Symposium , 2003 /9 /25 ~ 2003 /9 /26 .
  40. Wen-Hsiung Chan, Chih-Ching Wu, Jau-Song Yu , “Inhibition of UV irradiation-induced cytochrome C release and apoptotic biochemical changes in human epidermal carcinoma A431 cells by curcumin.” , 2003 , 2nd NHRI signal transduction conference , 2003 /3 /7 ~ 2003 /3 /8 .
  41. 詹文雄 , “細胞內氧化壓力的測定” , 2002 , 桃園地區大學院校研發成果聯合發表會 , 2002 /9 /14 ~ 2002 /9 /14 .
  42. Hsuuw, YD, Doong, JY, Chang, CK, Chan, W.-H. , “Selective effect of ethanol on embryonic cell growth and cell death in vivo” , 2001 , 17th International Congress of Nutrition , 2001 ~ 2004 .
  43. Chan, W.-H., Yu, J.-S. , “Inhibition of UV irradiation-induced oxidative stresses and apoptotic biochemical changes in human epidermal carcinoma A431 cells by genistein. ” , 2001 , 1st NHRI signal transduction conference , 2004 ~ 2004 .
部分專書
  1. 詹文雄 , “細胞的奈米構造和應用奈米科技偵測酵素動力學” , 奈米科技導論 , 高立圖書出版社 , 2004 .